Adaptation of the adrenal medulla to stress: Pathophysiological implications

There is no life without stress and adaptation to there life. Adaptation requires the intervention of nervous system for proper coordination adjustment intensity response stressful stimuli (stressors). The sympathetic primarily responsible rapid adaptive responses stress, which classic example “fight or flight” response. This mediated by adrenaline secreted from adrenal medulla noradrenaline released both postganglionic neurons. However, inadequate activation, in duration intensity, may be at origin several “stress-related” diseases (hypertension, heart failure, pain, etc.). Although has traditionally been viewed as a one functional unit, idea differentiated contribution between neurons, also with pathophysiological implications, gradually gaining ground. Keywords: stress; system; medulla; chromaffin cell; stress-related